Did you know that Glioblastoma multiforme is the most common and most aggressive type of primary brain tumor in humans, involving glial cells and accounting for 52% of all parenchymal brain tumor cases and 20% of all intracranial tumors?
Did you know that Glioblastoma multiforme is the most prevalent form of primary brain tumor, GBMs occur in only 2–3 cases per 100,000 people in Europe and North America?
According to the WHO classification of the tumors of the central nervous system, the standard name for this brain tumor is "glioblastoma"; it presents two variants: giant cell glioblastoma andgliosarcoma.
Did you know that Glioblastomas are also an important brain tumor of the canine, and research is ongoing to use this as a model for developing treatments in humans?[1]
Did you know that treatment can involve chemotherapy, radiation, radiosurgery, corticosteroids, antiangiogenic therapy, and surgery?[2]
Did you know that common symptoms of the disease include seizure, nausea and vomiting, headache, and hemiparesis, the single most prevalent symptom is a progressive memory, personality, or neurological deficit due to temporal and frontal lobe involvement?
Did you know that the kind of symptoms produced depends highly on the location of the tumor, more so than on its pathological properties?
Did you know that the tumor can start producing symptoms quickly, but occasionally is an asymptomatic condition until it reaches an enormous size?
Did you know that GBM is more common in males, although the reason for this is not clear?
Did you know that most glioblastoma tumors appear to be sporadic, without anygenetic predisposition?
Did you know that no links have been found between glioblastoma and smoking,[5] diet,[6] cellular phones,[7] or electromagnetic fields?[8]
Did you know that there also appears to be a small link between ionizing radiation and glioblastoma?[11]
Did you know that some believe that there may be a link between polyvinyl chloride (which is commonly used in construction) and glioblastoma?[12]
Did you know that a recent link cited in the Lancet medical journal links brain cancer to lead exposure in the work place?[13]
Did you know that there is an association of brain tumor incidence and malaria, suggesting that the anopheles mosquito, the carrier of malaria, might transmit a virus or other agent that could cause glioblastoma?[14]
Did you know that these are other risk factors include:[15]
- Sex: male (slightly more common in men than women)
- Age: over 50 years old
- Ethnicity: Caucasians, Latinos, Asians
- Having a low-grade astrocytoma (brain tumor), which often, given enough time, develops into a higher-grade tumor
- Having one of the following genetic disorders is associated with an increased incidence of gliomas: Neurofibromatosis, Tuberous sclerosis,Von Hippel-Lindau disease, Li-Fraumeni syndrome, Turcot syndrome
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